{"id":9469,"date":"2023-07-22T06:05:36","date_gmt":"2023-07-22T06:05:36","guid":{"rendered":"https:\/\/ivolabs.com\/?post_type=product&p=9469"},"modified":"2025-10-09T03:06:23","modified_gmt":"2025-10-09T03:06:23","slug":"nervigesic-pregabalin-150-eu2","status":"publish","type":"product","link":"https:\/\/ivolabs.com\/de\/produkt\/nervigesic-pregabalin-150-eu2\/","title":{"rendered":"Nervigesic Pregabalin 150 EU"},"content":{"rendered":"
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Product Description: Pregabalin<\/strong><\/p>\n

Pregabalin, often known by its brand name Lyrica, is a medication used to treat a range of conditions such as epilepsy, fibromyalgia, neuropathic pain, and generalized anxiety disorder (GAD). This substance falls under the classification of a gabapentinoid and is listed as a prescription-only medication in most countries. Pregabalin operates as an analgesic, anxiolytic, depressant, anticonvulsant, and, interestingly, has also been found to possess nootropic effects.<\/p>\n

As a gabapentinoid, pregabalin works primarily at the \u03b12\u03b4 (alpha-2-delta) subunit-containing voltage-dependent calcium channels in the central nervous system. It does not bind directly to GABA receptors but increases the density of GABA transporters, enhancing GABAergic transmission, which can influence the overall neurological activity. Additionally, it also reduces the release of several neurotransmitters, including glutamate, norepinephrine, and substance P.<\/p>\n

Pregabalin has a similar chemical structure to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), although it does not directly stimulate the GABA receptors or influence GABA uptake or degradation. It is also noteworthy that, unlike some other medicines used to treat seizure disorders, pregabalin does not have any known sodium channel activity or negative effects on dopamine receptors.<\/p>\n

Uses and Indications<\/strong><\/p>\n

Pregabalin has several applications in the medical field due to its varied effects. It has approval for the treatment of the following conditions:<\/p>\n

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  1. Neuropathic Pain:<\/strong> This is a form of chronic pain caused by damage to the nerves. Pregabalin is indicated for adults to treat peripheral and central neuropathic pain.<\/li>\n
  2. Epilepsy:<\/strong> It is used as an adjunctive therapy in adults with partial seizures with or without secondary generalization.<\/li>\n
  3. Generalized Anxiety Disorder (GAD):<\/strong> Pregabalin has demonstrated efficacy in treating GAD in adults.<\/li>\n
  4. Fibromyalgia:<\/strong> It is approved for the management of fibromyalgia, a condition characterized by chronic widespread pain and heightened pain response to pressure.<\/li>\n<\/ol>\n

    Dosage<\/strong><\/p>\n

    The dosage of pregabalin depends on the individual and the condition being treated. Always follow the guidance of a healthcare provider for accurate dosage information. However, general guidelines suggest the following:<\/p>\n

    For Neuropathic pain, the recommended starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose of pregabalin for treating neuropathic pain is 600 mg per day.<\/p>\n

    For treating epilepsy, the starting dose can be 75 mg two times a day or 50 mg three times a day. This dose can be increased to a maximum dose of 600 mg per day if necessary and if the patient can tolerate it.<\/p>\n

    In treating generalized anxiety disorder, the dose may start from 75 mg two times a day and can be increased to 150 mg two times a day within one week if the patient can tolerate the medication and requires more symptom relief. The maximum dose for GAD is 600 mg per day.<\/p>\n

    For fibromyalgia, the typical starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose for fibromyalgia is 450 mg per day.<\/p>\n

    It’s crucial to note that if pregabalin must be discontinued, it should be done gradually over a minimum of one week to lessen the potential of increased seizure frequency in patients with seizure disorders. Abrupt or rapid discontinuation may also precipitate withdrawal symptoms.<\/p>\n

    Safety and Precautions<\/strong><\/p>\n

    Patients should be advised to take precautions while using pregabalin, as it can cause dizziness and somnolence, which may increase the occurrence of accidental injury (fall) in the elderly population. It may also lead to other adverse effects, such as weight gain, blurred vision, dry mouth, and swelling in the hands or feet.<\/p>\n

    Pregabalin is eliminated from the systemic circulation primarily by renal excretion as unchanged drug. So, patients with decreased renal function or undergoing hemodialysis may require a lower dose of pregabalin due to the decreased renal clearance.<\/p>\n

    There are also some contraindications to the use of pregabalin. It should not be used in patients with a known hypersensitivity to pregabalin or any of its other components. Care should also be taken when prescribing pregabalin to patients with a history of substance abuse due to the potential for misuse and dependence.<\/p>\n

    Pregabalin should be used with caution in patients with congestive heart failure as it can cause peripheral edema. It’s also recommended to monitor patients for signs of suicidal ideation and behavior and to seek medical treatment if such symptoms occur.<\/p>\n

    Conclusion<\/strong><\/p>\n

    In conclusion, pregabalin is a versatile and effective medication for various conditions, including neuropathic pain, epilepsy, GAD, and fibromyalgia. It should always be used as directed by a healthcare professional, considering the potential for side effects and interactions with other medications. Regular monitoring and communication with the healthcare provider can ensure safe and effective use of this medication.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Produkt-Highlight: Pregabalin, das vielseitige Medikament
    \n<\/strong>Das Leben mit chronischen Schmerzen, Krampfanf\u00e4llen oder Angstzust\u00e4nden kann eine unglaubliche Herausforderung sein. Die gute Nachricht ist, dass es ein Medikament gibt, das genau die Hilfe sein k\u00f6nnte, die Sie brauchen. Darf ich vorstellen: Pregabalin, ein vielseitiges verschreibungspflichtiges Medikament, das das Leben auf der ganzen Welt ver\u00e4ndert.<\/p>\n

    Was ist Pregabalin?
    \n<\/strong>Pregabalin, allgemein bekannt unter seinem Markennamen Lyrica, ist ein Medikament, das zu einer Gruppe von Arzneimitteln geh\u00f6rt, die Gabapentinoide genannt werden. Es ist ein Allrounder in der Medizin, der eine Reihe von Krankheiten wie Epilepsie, Fibromyalgie (langfristige k\u00f6rperweite Schmerzen), Nervenschmerzen und generalisierte Angstst\u00f6rung (GAD) behandelt.<\/p>\n

    Auch wenn sein Name recht technisch klingt, funktioniert Pregabalin auf einfache Weise. Es beruhigt \u00fcberaktive Nervenzellen in Ihrem Gehirn und R\u00fcckenmark, die Krampfanf\u00e4lle, Schmerzen oder Angstzust\u00e4nde verursachen k\u00f6nnen.<\/p>\n

    Was kann Pregabalin f\u00fcr Sie tun?
    \n<\/strong>Wenn Sie mit Nervenschmerzen zu k\u00e4mpfen haben, sei es aufgrund einer Verletzung, einer Operation oder einer Erkrankung wie Diabetes, kann Pregabalin helfen, indem es die Schmerzmeldungen, die Ihre Nerven an Ihr Gehirn senden, d\u00e4mpft. Das bedeutet, dass Sie m\u00f6glicherweise Erleichterung von den st\u00e4ndigen, qu\u00e4lenden Schmerzen finden k\u00f6nnen, die Sie daran hindern, Ihr Leben voll auszuleben.<\/p>\n

    F\u00fcr Menschen mit Epilepsie, einer Erkrankung, die durch h\u00e4ufige Anf\u00e4lle gekennzeichnet ist, kann Pregabalin ein verl\u00e4sslicher Partner f\u00fcr Ihre Hauptmedikation gegen Epilepsie sein. Es kann helfen, die Anf\u00e4lle zu kontrollieren und erm\u00f6glicht es Ihnen, Ihren t\u00e4glichen Aktivit\u00e4ten nachzugehen, ohne sich Sorgen zu machen, wann der n\u00e4chste Anfall kommen k\u00f6nnte.<\/p>\n

    Leiden Sie an Fibromyalgie? Pregabalin kann helfen, die weit verbreiteten Schmerzen und Empfindlichkeiten zu lindern, die diese Erkrankung mit sich bringt. Es kann auch bei anderen Fibromyalgiesymptomen wie M\u00fcdigkeit und Schlafproblemen helfen.<\/p>\n

    Wenn Sie mit einer generalisierten Angstst\u00f6rung zu k\u00e4mpfen haben, k\u00f6nnte Pregabalin eine entscheidende Rolle spielen. Es kann dazu beitragen, ein Gef\u00fchl der Ruhe und Kontrolle zu vermitteln, das Angstgef\u00fchle reduziert und es Ihnen erm\u00f6glicht, das Leben mit mehr Leichtigkeit zu meistern.<\/p>\n

    Wir versenden KEINE EU-Medikamente in die Niederlande, nach D\u00e4nemark, Finnland, Schweden und Norwegen.<\/strong><\/p>","protected":false},"featured_media":15983,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[157,276],"product_tag":[429,431,428,425,422,423,426,424,420,432,421,427,430,347,433,419,435,434,364,436,384],"class_list":["post-9469","product","type-product","status-publish","has-post-thumbnail","product_cat-eu-meds","product_cat-painkiller-eu","product_tag-anticonvulsant-medicine","product_tag-anxiety-relief","product_tag-anxiolytic-drug","product_tag-chronic-pain-control","product_tag-epilepsy-treatment","product_tag-fibromyalgia-management","product_tag-gabapentinoid","product_tag-generalized-anxiety-disorder","product_tag-lyrica-drug","product_tag-lyrica-uses","product_tag-nerve-pain-relief","product_tag-neuropathic-pain-treatment","product_tag-neuropathy-therapy","product_tag-pain-management","product_tag-pregabalin-dosage","product_tag-pregabalin-medication","product_tag-pregabalin-safety","product_tag-pregabalin-side-effects","product_tag-prescription-medication","product_tag-sandoz-pregabalin","product_tag-seizure-control","first","outofstock","sale","shipping-taxable","purchasable","product-type-variable","has-default-attributes"],"_links":{"self":[{"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/product\/9469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/comments?post=9469"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/media\/15983"}],"wp:attachment":[{"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/media?parent=9469"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/product_brand?post=9469"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/product_cat?post=9469"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/ivolabs.com\/de\/wp-json\/wp\/v2\/product_tag?post=9469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}