{"id":9469,"date":"2023-07-22T06:05:36","date_gmt":"2023-07-22T06:05:36","guid":{"rendered":"https:\/\/ivolabs.com\/?post_type=product&p=9469"},"modified":"2025-10-09T03:06:23","modified_gmt":"2025-10-09T03:06:23","slug":"nervigesic-pregabalin-150-eu2","status":"publish","type":"product","link":"https:\/\/ivolabs.com\/fi\/tuote\/nervigesic-pregabalin-150-eu2\/","title":{"rendered":"Nervigesic Pregabalin 150 EU"},"content":{"rendered":"
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Product Description: Pregabalin<\/strong><\/p>\n

Pregabalin, often known by its brand name Lyrica, is a medication used to treat a range of conditions such as epilepsy, fibromyalgia, neuropathic pain, and generalized anxiety disorder (GAD). This substance falls under the classification of a gabapentinoid and is listed as a prescription-only medication in most countries. Pregabalin operates as an analgesic, anxiolytic, depressant, anticonvulsant, and, interestingly, has also been found to possess nootropic effects.<\/p>\n

As a gabapentinoid, pregabalin works primarily at the \u03b12\u03b4 (alpha-2-delta) subunit-containing voltage-dependent calcium channels in the central nervous system. It does not bind directly to GABA receptors but increases the density of GABA transporters, enhancing GABAergic transmission, which can influence the overall neurological activity. Additionally, it also reduces the release of several neurotransmitters, including glutamate, norepinephrine, and substance P.<\/p>\n

Pregabalin has a similar chemical structure to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), although it does not directly stimulate the GABA receptors or influence GABA uptake or degradation. It is also noteworthy that, unlike some other medicines used to treat seizure disorders, pregabalin does not have any known sodium channel activity or negative effects on dopamine receptors.<\/p>\n

Uses and Indications<\/strong><\/p>\n

Pregabalin has several applications in the medical field due to its varied effects. It has approval for the treatment of the following conditions:<\/p>\n

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  1. Neuropathic Pain:<\/strong> This is a form of chronic pain caused by damage to the nerves. Pregabalin is indicated for adults to treat peripheral and central neuropathic pain.<\/li>\n
  2. Epilepsy:<\/strong> It is used as an adjunctive therapy in adults with partial seizures with or without secondary generalization.<\/li>\n
  3. Generalized Anxiety Disorder (GAD):<\/strong> Pregabalin has demonstrated efficacy in treating GAD in adults.<\/li>\n
  4. Fibromyalgia:<\/strong> It is approved for the management of fibromyalgia, a condition characterized by chronic widespread pain and heightened pain response to pressure.<\/li>\n<\/ol>\n

    Dosage<\/strong><\/p>\n

    The dosage of pregabalin depends on the individual and the condition being treated. Always follow the guidance of a healthcare provider for accurate dosage information. However, general guidelines suggest the following:<\/p>\n

    For Neuropathic pain, the recommended starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose of pregabalin for treating neuropathic pain is 600 mg per day.<\/p>\n

    For treating epilepsy, the starting dose can be 75 mg two times a day or 50 mg three times a day. This dose can be increased to a maximum dose of 600 mg per day if necessary and if the patient can tolerate it.<\/p>\n

    In treating generalized anxiety disorder, the dose may start from 75 mg two times a day and can be increased to 150 mg two times a day within one week if the patient can tolerate the medication and requires more symptom relief. The maximum dose for GAD is 600 mg per day.<\/p>\n

    For fibromyalgia, the typical starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose for fibromyalgia is 450 mg per day.<\/p>\n

    It’s crucial to note that if pregabalin must be discontinued, it should be done gradually over a minimum of one week to lessen the potential of increased seizure frequency in patients with seizure disorders. Abrupt or rapid discontinuation may also precipitate withdrawal symptoms.<\/p>\n

    Safety and Precautions<\/strong><\/p>\n

    Patients should be advised to take precautions while using pregabalin, as it can cause dizziness and somnolence, which may increase the occurrence of accidental injury (fall) in the elderly population. It may also lead to other adverse effects, such as weight gain, blurred vision, dry mouth, and swelling in the hands or feet.<\/p>\n

    Pregabalin is eliminated from the systemic circulation primarily by renal excretion as unchanged drug. So, patients with decreased renal function or undergoing hemodialysis may require a lower dose of pregabalin due to the decreased renal clearance.<\/p>\n

    There are also some contraindications to the use of pregabalin. It should not be used in patients with a known hypersensitivity to pregabalin or any of its other components. Care should also be taken when prescribing pregabalin to patients with a history of substance abuse due to the potential for misuse and dependence.<\/p>\n

    Pregabalin should be used with caution in patients with congestive heart failure as it can cause peripheral edema. It’s also recommended to monitor patients for signs of suicidal ideation and behavior and to seek medical treatment if such symptoms occur.<\/p>\n

    Conclusion<\/strong><\/p>\n

    In conclusion, pregabalin is a versatile and effective medication for various conditions, including neuropathic pain, epilepsy, GAD, and fibromyalgia. It should always be used as directed by a healthcare professional, considering the potential for side effects and interactions with other medications. Regular monitoring and communication with the healthcare provider can ensure safe and effective use of this medication.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Tuotteen kohokohta: Pregabaliini, monipuolinen l\u00e4\u00e4ke
    \n<\/strong>Kroonisen kivun, kohtausten tai ahdistuksen kanssa el\u00e4minen voi olla uskomattoman haastavaa. Hyv\u00e4 uutinen on, ett\u00e4 on olemassa l\u00e4\u00e4kitys, joka saattaa olla juuri se auttava k\u00e4si, jota tarvitset. Tutustu Pregabaliiniin, monipuoliseen reseptil\u00e4\u00e4kkeeseen, joka muuttaa el\u00e4m\u00e4\u00e4 ymp\u00e4ri maailmaa.<\/p>\n

    Mit\u00e4 Pregabaliini on?
    \n<\/strong>Pregabaliini, joka tunnetaan yleisesti tuotenimell\u00e4 Lyrica, on l\u00e4\u00e4kitys, joka kuuluu l\u00e4\u00e4kkeiden ryhm\u00e4\u00e4n, jota kutsutaan gabapentinoideiksi. Se on l\u00e4\u00e4ketieteen monitaituri, joka hoitaa erilaisia sairauksia, kuten epilepsiaa, fibromyalgiaa (pitk\u00e4aikainen koko kehon laajuinen kipu), hermokipua ja yleistynytt\u00e4 ahdistuneisuush\u00e4iri\u00f6t\u00e4 (GAD).<\/p>\n

    Vaikka sen nimi saattaa kuulostaa varsin tekniselt\u00e4, Pregabaliini toimii yksinkertaisella tavalla. Se rauhoittaa aivojen ja selk\u00e4ytimen yliaktiivisia hermosoluja, jotka voivat aiheuttaa kohtauksia, kipua tai ahdistusta.<\/p>\n

    Mit\u00e4 Pregabaliini voi tehd\u00e4 sinulle?
    \n<\/strong>Jos sinulla on hermokipuja, jotka johtuvat vammasta, leikkauksesta tai sairaudesta, kuten diabeteksesta, Pregabaliini voi auttaa tylsytt\u00e4m\u00e4ll\u00e4 hermojen aivoihin l\u00e4hett\u00e4mi\u00e4 kipuviestej\u00e4. T\u00e4m\u00e4 tarkoittaa, ett\u00e4 voit mahdollisesti saada helpotusta jatkuvaan, nalkuttavaan kipuun, joka on est\u00e4nyt sinua el\u00e4m\u00e4st\u00e4 el\u00e4m\u00e4\u00e4si t\u00e4ysipainoisesti.<\/p>\n

    Niille, joilla on epilepsia, sairaus, jolle on ominaista usein esiintyv\u00e4t kohtaukset, Pregabaliini voi toimia luotettavana apulaisena p\u00e4\u00e4asiallisen epilepsial\u00e4\u00e4kityksen rinnalla. Se voi auttaa hallitsemaan kohtauksia ja antaa sinulle mahdollisuuden jatkaa p\u00e4ivitt\u00e4isi\u00e4 toimintojasi ilman huolta siit\u00e4, milloin seuraava kohtaus iskee.<\/p>\n

    K\u00e4rsitk\u00f6 fibromyaliasta? Pregabaliini voi auttaa lievitt\u00e4m\u00e4\u00e4n t\u00e4m\u00e4n sairauden aiheuttamaa laajalle levinnytt\u00e4 kipua ja arkuutta. Se saattaa auttaa my\u00f6s muihin fibromyalgian oireisiin, kuten v\u00e4symykseen ja uniongelmiin.<\/p>\n

    Lopuksi, jos taistelet yleistynytt\u00e4 ahdistuneisuush\u00e4iri\u00f6t\u00e4 vastaan, Pregabaliini voi olla ratkaiseva l\u00e4\u00e4ke. Se voi auttaa saamaan aikaan rauhallisuuden ja hallinnan tunteen, v\u00e4hent\u00e4\u00e4 ahdistuneisuuden tunteita ja antaa sinulle mahdollisuuden navigoida el\u00e4m\u00e4ss\u00e4 helpommin.<\/p>\n

    Emme l\u00e4het\u00e4 EU-l\u00e4\u00e4kkeit\u00e4 Alankomaihin, Tanskaan, Suomeen, Ruotsiin ja Norjaan.<\/strong><\/p>","protected":false},"featured_media":15983,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[157,276],"product_tag":[429,431,428,425,422,423,426,424,420,432,421,427,430,347,433,419,435,434,364,436,384],"class_list":["post-9469","product","type-product","status-publish","has-post-thumbnail","product_cat-eu-meds","product_cat-painkiller-eu","product_tag-anticonvulsant-medicine","product_tag-anxiety-relief","product_tag-anxiolytic-drug","product_tag-chronic-pain-control","product_tag-epilepsy-treatment","product_tag-fibromyalgia-management","product_tag-gabapentinoid","product_tag-generalized-anxiety-disorder","product_tag-lyrica-drug","product_tag-lyrica-uses","product_tag-nerve-pain-relief","product_tag-neuropathic-pain-treatment","product_tag-neuropathy-therapy","product_tag-pain-management","product_tag-pregabalin-dosage","product_tag-pregabalin-medication","product_tag-pregabalin-safety","product_tag-pregabalin-side-effects","product_tag-prescription-medication","product_tag-sandoz-pregabalin","product_tag-seizure-control","first","outofstock","sale","shipping-taxable","purchasable","product-type-variable","has-default-attributes"],"_links":{"self":[{"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/product\/9469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/comments?post=9469"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/media\/15983"}],"wp:attachment":[{"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/media?parent=9469"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/product_brand?post=9469"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/product_cat?post=9469"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/ivolabs.com\/fi\/wp-json\/wp\/v2\/product_tag?post=9469"}],"curies":[{"name":"hp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}