{"id":16111,"date":"2025-06-02T02:46:45","date_gmt":"2025-06-02T02:46:45","guid":{"rendered":"https:\/\/ivolabs.com\/?post_type=product&#038;p=16111"},"modified":"2026-05-31T11:17:07","modified_gmt":"2026-05-31T11:17:07","slug":"o-pcp-eu","status":"publish","type":"product","link":"https:\/\/ivolabs.com\/fr\/produit\/o-pcp-eu\/","title":{"rendered":"o-PCP UE"},"content":{"rendered":"<h3 data-start=\"279\" data-end=\"376\"><strong data-start=\"283\" data-end=\"376\">o-PCP (2-Keto-Phencyclidine): A Next-Gen Dissociative for Advanced Neurochemical Research<\/strong><\/h3>\n<hr data-start=\"378\" data-end=\"381\" \/>\n<h3 data-start=\"383\" data-end=\"404\">\ud83e\uddec What is o-PCP?<\/h3>\n<p data-start=\"406\" data-end=\"711\"><strong data-start=\"406\" data-end=\"415\">o-PCP<\/strong>, short for <strong data-start=\"427\" data-end=\"450\">ortho-Phencyclidine<\/strong> or <strong data-start=\"454\" data-end=\"468\">2-keto-PCP<\/strong>, is a novel arylcyclohexylamine dissociative, chemically related to <strong data-start=\"537\" data-end=\"544\">PCP<\/strong> and <strong data-start=\"549\" data-end=\"562\">3-MeO-PCP<\/strong>. It features a ketone group at the <strong data-start=\"598\" data-end=\"621\">ortho (2-) position<\/strong> on the cyclohexyl ring, setting it apart in both structure and receptor binding affinity.<\/p>\n<p data-start=\"713\" data-end=\"969\">Like other compounds in this class, o-PCP acts primarily as a <strong data-start=\"775\" data-end=\"819\">non-competitive NMDA receptor antagonist<\/strong>, interrupting glutamatergic neurotransmission and producing effects ranging from <strong data-start=\"901\" data-end=\"927\">analgesia and sedation<\/strong> to <strong data-start=\"931\" data-end=\"968\">detachment and sensory alteration<\/strong>.<\/p>\n<hr data-start=\"971\" data-end=\"974\" \/>\n<h3 data-start=\"976\" data-end=\"1014\">\ud83e\uddea Chemical and Structural Details<\/h3>\n<ul data-start=\"1016\" data-end=\"1294\">\n<li data-start=\"1016\" data-end=\"1074\">\n<p data-start=\"1018\" data-end=\"1074\"><strong data-start=\"1018\" data-end=\"1032\">Full Name:<\/strong> 1-[1-(2-Oxocyclohexyl)phenyl]piperidine<\/p>\n<\/li>\n<li data-start=\"1075\" data-end=\"1110\">\n<p data-start=\"1077\" data-end=\"1110\"><strong data-start=\"1077\" data-end=\"1099\">Molecular Formula:<\/strong> C17H23NO<\/p>\n<\/li>\n<li data-start=\"1111\" data-end=\"1149\">\n<p data-start=\"1113\" data-end=\"1149\"><strong data-start=\"1113\" data-end=\"1134\">Molecular Weight:<\/strong> 257.37 g\/mol<\/p>\n<\/li>\n<li data-start=\"1150\" data-end=\"1195\">\n<p data-start=\"1152\" data-end=\"1195\"><strong data-start=\"1152\" data-end=\"1167\">CAS Number:<\/strong> Unregistered (as of 2025)<\/p>\n<\/li>\n<li data-start=\"1196\" data-end=\"1239\">\n<p data-start=\"1198\" data-end=\"1239\"><strong data-start=\"1198\" data-end=\"1217\">Chemical Class:<\/strong> Arylcyclohexylamine<\/p>\n<\/li>\n<li data-start=\"1240\" data-end=\"1294\">\n<p data-start=\"1242\" data-end=\"1294\"><strong data-start=\"1242\" data-end=\"1251\">Form:<\/strong> Typically crystalline powder or fine solid<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1296\" data-end=\"1490\">The defining feature is its <strong data-start=\"1324\" data-end=\"1347\">2-keto substitution<\/strong>, which may affect <strong data-start=\"1366\" data-end=\"1395\">receptor binding kinetics<\/strong>, <strong data-start=\"1397\" data-end=\"1417\">lipid solubility<\/strong>, and <strong data-start=\"1423\" data-end=\"1448\">psychoactive duration<\/strong> when compared with 3-MeO-PCP or ketamine.<\/p>\n<hr data-start=\"1492\" data-end=\"1495\" \/>\n<h3 data-start=\"1497\" data-end=\"1523\">\u2699\ufe0f Mechanism of Action<\/h3>\n<p data-start=\"1525\" data-end=\"1742\">o-PCP acts as a <strong data-start=\"1541\" data-end=\"1576\">potent NMDA receptor antagonist<\/strong>, binding non-competitively to the PCP site on the NMDA ion channel. This disrupts calcium ion flow and <strong data-start=\"1680\" data-end=\"1727\">inhibits excitatory glutamatergic signaling<\/strong>, resulting in:<\/p>\n<ul data-start=\"1744\" data-end=\"1883\">\n<li data-start=\"1744\" data-end=\"1791\">\n<p data-start=\"1746\" data-end=\"1791\"><strong data-start=\"1746\" data-end=\"1791\">Disassociation from self and surroundings<\/strong><\/p>\n<\/li>\n<li data-start=\"1792\" data-end=\"1822\">\n<p data-start=\"1794\" data-end=\"1822\"><strong data-start=\"1794\" data-end=\"1822\">Analgesia and anesthesia<\/strong><\/p>\n<\/li>\n<li data-start=\"1823\" data-end=\"1849\">\n<p data-start=\"1825\" data-end=\"1849\"><strong data-start=\"1825\" data-end=\"1849\">Cognitive disruption<\/strong><\/p>\n<\/li>\n<li data-start=\"1850\" data-end=\"1883\">\n<p data-start=\"1852\" data-end=\"1883\"><strong data-start=\"1852\" data-end=\"1883\">Altered sensory integration<\/strong><\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1885\" data-end=\"2034\">This compound may also interact with dopamine, serotonin, or sigma receptors to a minor extent, though these interactions are not well-characterized.<\/p>\n<hr data-start=\"2036\" data-end=\"2039\" \/>\n<h3 data-start=\"2041\" data-end=\"2082\">\ud83d\udcca Effects Profile (Based on Analogs)<\/h3>\n<div class=\"_tableContainer_16hzy_1\">\n<div class=\"_tableWrapper_16hzy_14 group flex w-fit flex-col-reverse\" tabindex=\"-1\">\n<table class=\"w-fit min-w-(--thread-content-width)\" data-start=\"2084\" data-end=\"2349\">\n<thead data-start=\"2084\" data-end=\"2104\">\n<tr data-start=\"2084\" data-end=\"2104\">\n<th data-start=\"2084\" data-end=\"2093\" data-col-size=\"sm\">Domain<\/th>\n<th data-start=\"2093\" data-end=\"2104\" data-col-size=\"md\">Effects<\/th>\n<\/tr>\n<\/thead>\n<tbody data-start=\"2126\" data-end=\"2349\">\n<tr data-start=\"2126\" data-end=\"2179\">\n<td data-start=\"2126\" data-end=\"2137\" data-col-size=\"sm\">Physical<\/td>\n<td data-col-size=\"md\" data-start=\"2137\" data-end=\"2179\">Numbness, motor impairment, anesthesia<\/td>\n<\/tr>\n<tr data-start=\"2180\" data-end=\"2228\">\n<td data-start=\"2180\" data-end=\"2192\" data-col-size=\"sm\">Cognitive<\/td>\n<td data-col-size=\"md\" data-start=\"2192\" data-end=\"2228\">Dissociation, amnesia, confusion<\/td>\n<\/tr>\n<tr data-start=\"2229\" data-end=\"2286\">\n<td data-start=\"2229\" data-end=\"2239\" data-col-size=\"sm\">Sensory<\/td>\n<td data-col-size=\"md\" data-start=\"2239\" data-end=\"2286\">Visual distortions, tinnitus, time dilation<\/td>\n<\/tr>\n<tr data-start=\"2287\" data-end=\"2349\">\n<td data-start=\"2287\" data-end=\"2299\" data-col-size=\"sm\">Emotional<\/td>\n<td data-col-size=\"md\" data-start=\"2299\" data-end=\"2349\">Euphoria, detachment, paranoia (at high doses)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<h2>o-PCP (2-K\u00e9to-Ph\u00e9ncyclidine) \u2013 Antagoniste NMDA dissociatif puissant<\/h2>\n<p><strong>o-PCP<\/strong> est un produit chimique de recherche de la famille des arylcyclohexylamines, structurellement similaire au PCP mais avec une substitution 2-c\u00e9tone. Il agit comme un <strong>antagoniste non comp\u00e9titif des r\u00e9cepteurs NMDA<\/strong>, produisant des effets dissociatifs, analg\u00e9siques et alt\u00e9rant la cognition.<\/p>\n<ul>\n<li>Longue dur\u00e9e et tr\u00e8s puissant<\/li>\n<li>Distinct du 3-MeO-PCP ou de la k\u00e9tamine<\/li>\n<li>Pr\u00e9cieux pour les \u00e9tudes sur les r\u00e9cepteurs NMDA et la conscience<\/li>\n<\/ul>\n<p><em>L'o-PCP n'est pas destin\u00e9 \u00e0 la consommation humaine. Pour usage de recherche et m\u00e9dico-l\u00e9gal uniquement. Manipuler avec pr\u00e9caution.<\/em><\/p>\n<p><strong>Ceci, comme tous les produits de EU RC, est exp\u00e9di\u00e9 deux fois par semaine par courrier express sans num\u00e9ro de suivi, <\/strong><br \/>\n<strong>vers les pays europ\u00e9ens UNIQUEMENT.<\/strong><\/p>","protected":false},"featured_media":16115,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[164,182],"product_tag":[1119,1134,1122,682,848,1127,1121,1126,1125,1123,1132,1130,849,1133,1118,1131,1120,1129,1124,1128],"class_list":["post-16111","product","type-product","status-publish","has-post-thumbnail","product_cat-europe-stock","product_cat-disso-psy","product_tag-2-keto-pcp","product_tag-analgesic-analog","product_tag-arylcyclohexylamine","product_tag-consciousness-research","product_tag-dissociative-anesthetic","product_tag-dissociative-pharmacology","product_tag-dissociative-research-chemical","product_tag-experimental-nmda-blocker","product_tag-glutamate-inhibitor","product_tag-ketone-substituted-pcp","product_tag-long-acting-dissociative","product_tag-neurochemical-modulation","product_tag-nmda-antagonist","product_tag-nmda-receptor-study","product_tag-o-pcp","product_tag-pcp-derivative","product_tag-phencyclidine-analog","product_tag-psychotomimetic-agent","product_tag-research-dissociative","product_tag-synthetic-arylcyclohexylamine","product_shipping_class-eu-chems","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product\/16111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/comments?post=16111"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/media\/16115"}],"wp:attachment":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/media?parent=16111"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_brand?post=16111"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_cat?post=16111"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_tag?post=16111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}