{"id":9469,"date":"2023-07-22T06:05:36","date_gmt":"2023-07-22T06:05:36","guid":{"rendered":"https:\/\/ivolabs.com\/?post_type=product&p=9469"},"modified":"2025-10-09T03:06:23","modified_gmt":"2025-10-09T03:06:23","slug":"nervigesic-pregabalin-150-eu2","status":"publish","type":"product","link":"https:\/\/ivolabs.com\/fr\/produit\/nervigesic-pregabalin-150-eu2\/","title":{"rendered":"Nervigesic Pr\u00e9gabaline 150 UE"},"content":{"rendered":"
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Product Description: Pregabalin<\/strong><\/p>\n

Pregabalin, often known by its brand name Lyrica, is a medication used to treat a range of conditions such as epilepsy, fibromyalgia, neuropathic pain, and generalized anxiety disorder (GAD). This substance falls under the classification of a gabapentinoid and is listed as a prescription-only medication in most countries. Pregabalin operates as an analgesic, anxiolytic, depressant, anticonvulsant, and, interestingly, has also been found to possess nootropic effects.<\/p>\n

As a gabapentinoid, pregabalin works primarily at the \u03b12\u03b4 (alpha-2-delta) subunit-containing voltage-dependent calcium channels in the central nervous system. It does not bind directly to GABA receptors but increases the density of GABA transporters, enhancing GABAergic transmission, which can influence the overall neurological activity. Additionally, it also reduces the release of several neurotransmitters, including glutamate, norepinephrine, and substance P.<\/p>\n

Pregabalin has a similar chemical structure to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), although it does not directly stimulate the GABA receptors or influence GABA uptake or degradation. It is also noteworthy that, unlike some other medicines used to treat seizure disorders, pregabalin does not have any known sodium channel activity or negative effects on dopamine receptors.<\/p>\n

Uses and Indications<\/strong><\/p>\n

Pregabalin has several applications in the medical field due to its varied effects. It has approval for the treatment of the following conditions:<\/p>\n

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  1. Neuropathic Pain:<\/strong> This is a form of chronic pain caused by damage to the nerves. Pregabalin is indicated for adults to treat peripheral and central neuropathic pain.<\/li>\n
  2. Epilepsy:<\/strong> It is used as an adjunctive therapy in adults with partial seizures with or without secondary generalization.<\/li>\n
  3. Generalized Anxiety Disorder (GAD):<\/strong> Pregabalin has demonstrated efficacy in treating GAD in adults.<\/li>\n
  4. Fibromyalgia:<\/strong> It is approved for the management of fibromyalgia, a condition characterized by chronic widespread pain and heightened pain response to pressure.<\/li>\n<\/ol>\n

    Dosage<\/strong><\/p>\n

    The dosage of pregabalin depends on the individual and the condition being treated. Always follow the guidance of a healthcare provider for accurate dosage information. However, general guidelines suggest the following:<\/p>\n

    For Neuropathic pain, the recommended starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose of pregabalin for treating neuropathic pain is 600 mg per day.<\/p>\n

    For treating epilepsy, the starting dose can be 75 mg two times a day or 50 mg three times a day. This dose can be increased to a maximum dose of 600 mg per day if necessary and if the patient can tolerate it.<\/p>\n

    In treating generalized anxiety disorder, the dose may start from 75 mg two times a day and can be increased to 150 mg two times a day within one week if the patient can tolerate the medication and requires more symptom relief. The maximum dose for GAD is 600 mg per day.<\/p>\n

    For fibromyalgia, the typical starting dose is 75 mg two times a day, which can be increased to 150 mg two times a day within one week based on efficacy and tolerability. The maximum dose for fibromyalgia is 450 mg per day.<\/p>\n

    It’s crucial to note that if pregabalin must be discontinued, it should be done gradually over a minimum of one week to lessen the potential of increased seizure frequency in patients with seizure disorders. Abrupt or rapid discontinuation may also precipitate withdrawal symptoms.<\/p>\n

    Safety and Precautions<\/strong><\/p>\n

    Patients should be advised to take precautions while using pregabalin, as it can cause dizziness and somnolence, which may increase the occurrence of accidental injury (fall) in the elderly population. It may also lead to other adverse effects, such as weight gain, blurred vision, dry mouth, and swelling in the hands or feet.<\/p>\n

    Pregabalin is eliminated from the systemic circulation primarily by renal excretion as unchanged drug. So, patients with decreased renal function or undergoing hemodialysis may require a lower dose of pregabalin due to the decreased renal clearance.<\/p>\n

    There are also some contraindications to the use of pregabalin. It should not be used in patients with a known hypersensitivity to pregabalin or any of its other components. Care should also be taken when prescribing pregabalin to patients with a history of substance abuse due to the potential for misuse and dependence.<\/p>\n

    Pregabalin should be used with caution in patients with congestive heart failure as it can cause peripheral edema. It’s also recommended to monitor patients for signs of suicidal ideation and behavior and to seek medical treatment if such symptoms occur.<\/p>\n

    Conclusion<\/strong><\/p>\n

    In conclusion, pregabalin is a versatile and effective medication for various conditions, including neuropathic pain, epilepsy, GAD, and fibromyalgia. It should always be used as directed by a healthcare professional, considering the potential for side effects and interactions with other medications. Regular monitoring and communication with the healthcare provider can ensure safe and effective use of this medication.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Produit phare : La pr\u00e9gabaline, un m\u00e9dicament aux multiples facettes
    \n<\/strong>Vivre avec une douleur chronique, des crises d'\u00e9pilepsie ou de l'anxi\u00e9t\u00e9 peut \u00eatre incroyablement difficile. La bonne nouvelle, c'est qu'il existe un m\u00e9dicament qui pourrait bien \u00eatre le coup de pouce dont vous avez besoin. Voici la pr\u00e9gabaline, un m\u00e9dicament polyvalent d\u00e9livr\u00e9 sur ordonnance qui change des vies dans le monde entier.<\/p>\n

    Qu'est-ce que la pr\u00e9gabaline ?
    \n<\/strong>La pr\u00e9gabaline, plus connue sous le nom de Lyrica, est un m\u00e9dicament qui appartient \u00e0 un groupe de m\u00e9dicaments appel\u00e9s gabapentino\u00efdes. Il s'agit d'un m\u00e9dicament polyvalent qui s'attaque \u00e0 toute une s\u00e9rie d'affections telles que l'\u00e9pilepsie, la fibromyalgie (douleur corporelle de longue dur\u00e9e), les douleurs nerveuses et le trouble anxieux g\u00e9n\u00e9ralis\u00e9 (TAG).<\/p>\n

    M\u00eame si son nom peut sembler assez technique, la pr\u00e9gabaline agit de mani\u00e8re simple. Elle calme les cellules nerveuses hyperactives du cerveau et de la moelle \u00e9pini\u00e8re qui peuvent provoquer des crises, des douleurs ou de l'anxi\u00e9t\u00e9.<\/p>\n

    Que peut faire la pr\u00e9gabaline pour vous ?
    \n<\/strong>Si vous souffrez de douleurs nerveuses, qu'elles soient dues \u00e0 une blessure, \u00e0 une intervention chirurgicale ou \u00e0 une maladie comme le diab\u00e8te, la pr\u00e9gabaline peut vous aider en att\u00e9nuant les messages de douleur que vos nerfs envoient \u00e0 votre cerveau. Cela signifie que vous pourriez trouver un soulagement \u00e0 cette douleur constante et lancinante qui vous emp\u00eache de vivre pleinement votre vie.<\/p>\n

    Pour les personnes souffrant d'\u00e9pilepsie, une maladie caract\u00e9ris\u00e9e par des crises fr\u00e9quentes, la pr\u00e9gabaline peut \u00eatre un compl\u00e9ment fiable au traitement principal de l'\u00e9pilepsie. Elle peut aider \u00e0 contr\u00f4ler les crises et vous permettre de poursuivre vos activit\u00e9s quotidiennes sans vous soucier de la date de la prochaine crise.<\/p>\n

    Vous souffrez de fibromyalgie ? La pr\u00e9gabaline peut aider \u00e0 soulager la douleur et la sensibilit\u00e9 g\u00e9n\u00e9ralis\u00e9es qu'entra\u00eene cette affection. Elle peut \u00e9galement aider \u00e0 soulager d'autres sympt\u00f4mes de la fibromyalgie tels que la fatigue et les troubles du sommeil.<\/p>\n

    Enfin, si vous \u00eates aux prises avec un trouble anxieux g\u00e9n\u00e9ralis\u00e9, la pr\u00e9gabaline pourrait changer la donne. Elle peut vous aider \u00e0 retrouver un sentiment de calme et de ma\u00eetrise, en r\u00e9duisant les sentiments d'anxi\u00e9t\u00e9 et en vous permettant de naviguer dans la vie avec plus d'aisance.<\/p>\n

    Nous n'exp\u00e9dions pas de m\u00e9dicaments europ\u00e9ens aux Pays-Bas, au Danemark, en Finlande, en Su\u00e8de et en Norv\u00e8ge.<\/strong><\/p>","protected":false},"featured_media":15983,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[157,276],"product_tag":[429,431,428,425,422,423,426,424,420,432,421,427,430,347,433,419,435,434,364,436,384],"class_list":["post-9469","product","type-product","status-publish","has-post-thumbnail","product_cat-eu-meds","product_cat-painkiller-eu","product_tag-anticonvulsant-medicine","product_tag-anxiety-relief","product_tag-anxiolytic-drug","product_tag-chronic-pain-control","product_tag-epilepsy-treatment","product_tag-fibromyalgia-management","product_tag-gabapentinoid","product_tag-generalized-anxiety-disorder","product_tag-lyrica-drug","product_tag-lyrica-uses","product_tag-nerve-pain-relief","product_tag-neuropathic-pain-treatment","product_tag-neuropathy-therapy","product_tag-pain-management","product_tag-pregabalin-dosage","product_tag-pregabalin-medication","product_tag-pregabalin-safety","product_tag-pregabalin-side-effects","product_tag-prescription-medication","product_tag-sandoz-pregabalin","product_tag-seizure-control","first","outofstock","sale","shipping-taxable","purchasable","product-type-variable","has-default-attributes"],"_links":{"self":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product\/9469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/comments?post=9469"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/media\/15983"}],"wp:attachment":[{"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/media?parent=9469"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_brand?post=9469"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_cat?post=9469"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/ivolabs.com\/fr\/wp-json\/wp\/v2\/product_tag?post=9469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}