4-AcO-DMT, also known as O-Acetylpsilocin or psilacetin, is a synthetic psychedelic compound belonging to the tryptamine class. Structurally related to psilocybin and psilocin\u2014the active constituents of “magic mushrooms”\u20144-AcO-DMT is considered a prodrug of psilocin, meaning it metabolizes into psilocin in the body, producing similar psychoactive effects.<\/p>\n
Chemical Structure and Properties<\/strong><\/p>\n IUPAC Name<\/strong>: 3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl acetate<\/p>\n<\/li>\n Molecular Formula<\/strong>: C14H18N2O2<\/p>\n<\/li>\n Molecular Weight<\/strong>: 246.31 g\/mol<\/p>\n<\/li>\n CAS Number<\/strong>: 92292-84-7<\/p>\n<\/li>\n Appearance<\/strong>: Typically found as a white to off-white powder; may degrade to a brownish color over time due to oxidation or due different kind of synthesis.<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Pharmacology<\/strong><\/p>\n 4-AcO-DMT functions primarily as a serotonergic psychedelic, acting as a non-selective agonist at various serotonin receptors, notably the 5-HT2A receptor. Upon ingestion, it is rapidly deacetylated to psilocin, which then exerts its psychoactive effects.<\/p>\n Mechanism of Action<\/strong><\/p>\n As a prodrug, 4-AcO-DMT is converted into psilocin in the body. Psilocin binds to serotonin receptors, particularly 5-HT2A, leading to altered perception, mood, and cognition. This mechanism is similar to that of naturally occurring psychedelics like psilocybin.<\/p>\n Dosage Guidelines<\/strong><\/p>\n Dosage can vary based on individual sensitivity, method of administration, and desired intensity of effects. Oral ingestion is the most common route.<\/p>\n Threshold<\/strong>: 5\u201310 mg<\/p>\n<\/li>\n Light<\/strong>: 10\u201315 mg<\/p>\n<\/li>\n Common<\/strong>: 15\u201325 mg<\/p>\n<\/li>\n Strong<\/strong>: 25\u201340 mg<\/p>\n<\/li>\n Heavy<\/strong>: 40+ mg<\/p>\n<\/li>\n<\/ul>\n Duration of Effects<\/strong><\/p>\n Onset<\/strong>: 20\u201360 minutes<\/p>\n<\/li>\n Peak<\/strong>: 2\u20133 hours<\/p>\n<\/li>\n Total Duration<\/strong>: 4\u20136 hours<\/p>\n<\/li>\n After-effects<\/strong>: 1\u20132 hours<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Subjective Effects<\/strong><\/p>\n Users report a range of effects, including:<\/p>\n Enhanced visual and auditory perception<\/p>\n<\/li>\n Altered sense of time and self<\/p>\n<\/li>\n Emotional introspection<\/p>\n<\/li>\n Visual hallucinations<\/p>\n<\/li>\n Synesthesia<\/p>\n<\/li>\n Euphoria or anxiety, depending on set and setting<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Potential Side Effects<\/strong><\/p>\n While many users have positive experiences, potential side effects include:<\/p>\n Nausea<\/p>\n<\/li>\n Anxiety or paranoia<\/p>\n<\/li>\n Confusion<\/p>\n<\/li>\n Dizziness<\/p>\n<\/li>\n Increased heart rate<\/p>\n<\/li>\n Muscle tension<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Harm Reduction Practices<\/strong><\/p>\n Set and Setting<\/strong>: Ensure a comfortable environment and a positive mindset.<\/p>\n<\/li>\n Sitter<\/strong>: Having a sober, trusted individual present can enhance safety.<\/p>\n<\/li>\n Avoid Mixing<\/strong>: Do not combine with other substances, especially MAOIs or SSRIs.<\/p>\n<\/li>\n Start Low<\/strong>: Begin with a lower dose to assess individual sensitivity.<\/p>\n<\/li>\n Stay Hydrated<\/strong>: Drink water, but avoid excessive consumption.<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Legal Status<\/strong><\/p>\n The legal status of 4-AcO-DMT varies by country:<\/p>\n United States<\/strong>: Not scheduled federally but may be considered an analog of psilocin under the Federal Analogue Act.<\/p>\n<\/li>\n United Kingdom<\/strong>: Classified as a Class A substance.<\/p>\n<\/li>\n Germany<\/strong>: Controlled under the New Psychoactive Substances Act (NpSG).<\/p>\n<\/li>\n Canada<\/strong>: Unscheduled but may be subject to analog laws.<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Storage and Stability<\/strong><\/p>\n 4-AcO-DMT is sensitive to moisture, heat, and light. To maintain potency:<\/p>\n Store in airtight containers<\/p>\n<\/li>\n Keep in a cool, dry, and dark place<\/p>\n<\/li>\n Use desiccants to reduce moisture<\/p>\n<\/li>\n<\/ul>\n <\/p>\n Conclusion<\/strong><\/p>\n 4-AcO-DMT offers a unique psychedelic experience, closely resembling that of psilocybin mushrooms. While it holds potential for research and personal exploration, users should approach with caution, adhering to harm reduction practices and being mindful of legal considerations.<\/p>\n","protected":false},"excerpt":{"rendered":" 4-AcO-DMT<\/strong>, ook bekend als psilacetine<\/em>, is een synthetische psychedelische stof die diepgaande introspectieve reizen biedt. Structureel vergelijkbaar met psilocybine, wordt het in het lichaam omgezet in psilocine, wat leidt tot transformerende ervaringen.<\/p>\n Ga op een innerlijke reis en verken de domeinen van je geest met 4-AcO-DMT.<\/p>\n Note:<\/em> Information here is provided for educational purposes only. Please follow local laws and guidelines for safe use.<\/p>\n This like all the products from EU RC are shipped on weekly by express mail without tracking number, <\/strong>\n
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Ervaar de Diepten van het Bewustzijn met 4-AcO-DMT<\/h2>\n
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