Lorazepam Hemofarm 2.5mg EU

1. Introduction

Lorazepam Hemofarm 2.5mg is a highly effective medication from the Hemofarm pharmaceutical group that belongs to the family of benzodiazepines. Its primary function is to act on the central nervous system to produce sedation, induce sleep, reduce anxiety, and muscle relaxation. This document provides an in-depth description of the product, its composition, indications, contraindications, potential side effects, and guidelines for appropriate usage.

2. Product Description

Each Lorazepam Hemofarm 2.5mg tablet contains 2.5mg of the active ingredient, Lorazepam. The other constituents include lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium. The tablet is typically round, white to off-white, and has a flat surface with beveled edges. The tablet comes in a blister pack of 10, 20, 30, 50, or 100 tablets.

3. Pharmacological Properties

Lorazepam is a benzodiazepine that exerts anxiolytic, sedative, hypnotic, amnesic, anticonvulsant, and muscle relaxant effects. It acts on the gamma-aminobutyric acid (GABA) neurotransmitter in the brain, enhancing its effects to reduce the activity of the neurons, thereby helping to calm the brain and nerves.

4. Indications

Lorazepam Hemofarm 2.5mg is indicated for the management of various conditions such as:

• Anxiety disorders and short-term relief of symptoms of anxiety
• Insomnia related to anxiety
• Premedication for minor surgical or diagnostic procedures
• Treatment of acute seizures and for the prevention of seizures related to certain medical procedures.

5. Contraindications

The use of Lorazepam Hemofarm 2.5mg is contraindicated in patients with:

• Hypersensitivity to lorazepam, other benzodiazepines, or any components of the product
• Severe respiratory insufficiency
• Sleep apnea syndrome
• Severe hepatic insufficiency
• Myasthenia gravis

6. Precautions for Use

While using Lorazepam Hemofarm 2.5mg, patients should be under the careful supervision of a healthcare provider, especially those with a history of drug or alcohol abuse. It is important to monitor for signs of psychological and physical dependence.

7. Interactions

Interactions can occur with alcohol, CNS depressants, certain antidepressants, antipsychotics, sedatives, antiepileptic drugs, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors, and analgesics. Such interactions can enhance the sedative effect of Lorazepam.

8. Side Effects

The most common side effects of Lorazepam Hemofarm 2.5mg include sedation, dizziness, weakness, unsteadiness, disorientation, depression, nausea, change in appetite, and sleep disturbances.

9. Overdose

In the event of an overdose, manifestations may include somnolence, confusion, dysarthria, paradoxical reactions, drowsiness, hypnotic state, coma, cardiovascular depression, respiratory failure, and death. If an overdose occurs, medical attention should be sought immediately.

10. Storage and Disposal

Lorazepam Hemofarm 2.5mg should be stored at a temperature below 30°C, away from moisture and light, and out of the reach of children