FOX04-DRI
€1,520.00
FOX04-DRI (FOXO4-D-Retro-Inverso) is a senolytic peptide that targets and eliminates senescent cells — aged, damaged cells that refuse to die and instead release inflammatory signals that damage surrounding tissue. By clearing these “zombie cells,” FOX04-DRI promotes tissue rejuvenation. Supplied as lyophilized powder with ≥98% purity (HPLC-verified).
How It Works
As we age, damaged cells enter a state called senescence. They don’t divide, but they don’t die either — they hang around releasing inflammatory chemicals that damage nearby healthy cells and accelerate aging. FOX04-DRI works by blocking the interaction between FOXO4 (a protein that keeps senescent cells alive) and p53 (the cell’s suicide switch). When this interaction is blocked, senescent cells finally undergo apoptosis — programmed cell death — making room for healthy cells.
Research Data
- Senescent cell clearance: Research demonstrates FOX04-DRI selectively kills senescent cells while leaving healthy cells untouched — the holy grail of senolytic therapy.
- Tissue rejuvenation: In aging mouse studies, FOX04-DRI treatment restored fur density (hair regrowth), improved kidney function, and increased spontaneous activity — effects consistent with multi-tissue rejuvenation.
- Chemotherapy recovery: Research shows FOX04-DRI counteracts chemotherapy-induced senescence and toxicity, reducing both the short-term damage and the long-term accelerated aging caused by cancer treatment.
- Frailty reduction: Senescent cell clearance is associated with improved physical function, grip strength, and overall vitality in aging models.
- Inflammaging: By removing senescent cells, FOX04-DRI reduces the chronic low-grade inflammation that characterizes aging — known as “inflammaging.”
- Life quality: Unlike lifespan extension studies that focus on maximum lifespan, FOX04-DRI focuses on healthspan — extending the period of healthy, functional life.
Research Applications
- Senolytic pharmacology and cellular senescence
- Aging and healthspan research
- Chemotherapy toxicity and recovery
- Inflammaging and chronic inflammation
Product Specifications
- Purity: ≥98% (HPLC)
- Form: Lyophilized powder
- Solubility: Reconstitute in sterile bacteriostatic water
Storage & Handling
- Store lyophilized peptide at -20°C, protected from light and moisture.
- After reconstitution, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.
Disclaimer: This product is intended exclusively for laboratory and research purposes. It is not a drug, dietary supplement, or food product. Not for human or veterinary use.
What the Internet Says
This is what online communities discuss. Not medical advice — for laboratory research use only.
Community Buzz
FOX04-DRI is “the zombie cell killer” — one of the most discussed longevity peptides in biohacking circles. As a senolytic, it selectively clears senescent “zombie” cells — old cells that refuse to die and instead leak inflammatory signals that age surrounding tissue. The community protocol: FOX04-DRI first (2mg EOD for 5 doses, then 5mg EOD for 8 doses) to clear senescent cells, then follow with BPC-157 and TB-500 for tissue recovery, then SS-31 and MOTS-C for mitochondrial health, and finally Thymalin and Epithalon for general longevity. The logic: clear the old cells first, then rebuild and protect what remains.
Why People Are Interested
- Clears senescent cells that drive aging. Zombie cells cause inflammation and tissue dysfunction — FOX04-DRI removes them.
- Reduces age-related inflammation. Fewer senescent cells = less inflammatory signaling throughout the body.
- First step in comprehensive longevity protocols. Clear old cells, then rebuild with healing and mitochondrial peptides.
⚠️ Senolytic therapy is experimental with no long-term human data. Community protocols are experimental. This information is for awareness only.
| Dosage |
10mg*10vials |
|---|
Shipping & Delivery
All peptide products are shipped directly from our fulfillment center in China.
Delivery Time: 6 to 12 business days worldwide.
Tracking: A tracking number is provided via email once your order has been dispatched.
For any questions regarding your shipment, please contact our support team.
All peptide products are supplied as a lyophilized (freeze-dried) powder in sterile glass vials. Lyophilization preserves the peptide's structural integrity and biological activity during transport and storage. The powder must be reconstituted with an appropriate solvent before use in research protocols.
Recommended Solvent
For most peptide research applications, we recommend using Bacteriostatic Water (BAC) — sterile water containing 0.9% benzyl alcohol as a bacteriostatic agent. BAC water helps maintain sterility after reconstitution and is suitable for multi-dose research protocols.
Order Bacteriostatic Water (BAC) →
Reconstitution Protocol
- Prepare: Clean your work surface and ensure all materials (vial, BAC water, syringes) are handled in a sterile manner.
- Calculate: Determine the desired concentration by dividing the peptide mass (mg) by the volume of BAC water added (mL). For example, adding 2 mL of BAC water to a 5 mg vial yields a concentration of 2.5 mg/mL.
- Reconstitute: Using a sterile syringe, draw the calculated volume of BAC water. Insert the needle through the rubber stopper at an angle and slowly inject the solvent down the inner wall of the vial — avoid directing the stream directly onto the powder to prevent foaming.
- Dissolve: Gently swirl the vial (do not shake) until the powder is fully dissolved. Most peptides dissolve within 1-2 minutes. A clear, colorless solution indicates complete dissolution.
- Aliquot: For long-term use, transfer the reconstituted solution into sterile aliquots to avoid repeated freeze-thaw cycles of the original vial.
Post-Reconstitution Storage
- Store reconstituted peptide solution at 2-8°C for short-term use (up to 7 days).
- For extended storage, aliquot and freeze at -20°C. Avoid repeated freeze-thaw cycles.
- Always label aliquots with peptide name, concentration, date, and storage conditions.
Note: The optimal solvent and reconstitution protocol may vary depending on the specific peptide and research application. Researchers should consult peptide-specific literature for solubility guidance.
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We maintain strict quality control standards with third-party laboratory verification for every batch. Our lyophilized peptides are packaged under controlled conditions to ensure stability during shipping and storage. Detailed reconstitution and handling information is provided with every product to support accurate laboratory research protocols.
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