CJC-1295 With DAC

CJC-1295 With DAC (Drug Affinity Complex) is a long-acting GHRH analogue with an extended half-life of approximately 8 days. The DAC component binds to albumin in the blood, creating a slow-release depot that keeps GH levels elevated around the clock. Supplied as lyophilized powder with ≥98% purity (HPLC-verified).

How It Works

The DAC tag attaches to albumin (the most abundant blood protein), protecting the peptide from rapid breakdown. This creates a constant GHRH-like signal to the pituitary, resulting in sustained — rather than pulsed — GH release. Think of it as the difference between sipping coffee all day versus one strong cup that wears off.

Research Data

• Extended half-life: Studies confirm a half-life of approximately 8 days, producing continuously elevated GH and IGF-1 levels.
• Sustained IGF-1: Research shows IGF-1 levels can remain elevated 200-300% above baseline for days after administration.
• Constant anabolic signal: Unlike pulsed GH release (the natural pattern), DAC provides a steady GH elevation that ensures muscles receive a continuous growth signal.
• Tissue repair: Constant GH elevation accelerates recovery from injury, with research showing faster tendon and bone healing in animal models.
• Muscle & fat effects: Lean mass increases and fat mass reductions are observed in research models, typical of sustained GH elevation.

Research Applications

• Sustained GHRH receptor pharmacology
• Continuous vs pulsatile GH release comparison
• Long-duration anabolic pathway research
• Albumin-conjugated peptide pharmacokinetics

Product Specifications

• Purity: ≥98% (HPLC)
• Form: Lyophilized powder
• Solubility: Reconstitute in sterile bacteriostatic water

Storage & Handling

• Store lyophilized peptide at -20°C, protected from light and moisture.
• After reconstitution, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.

Disclaimer: This product is intended exclusively for laboratory and research purposes. It is not a drug, dietary supplement, or food product. Not for human or veterinary use.

What the Internet Says

This is what online communities discuss about this compound. Not medical advice, not a recommendation — just what people are saying. For laboratory research use only.

Community Buzz

CJC-1295 With DAC is the longer-acting sibling in the CJC family. While the “without DAC” version (Mod GRF 1-29) acts in short 30-minute pulses, the DAC version binds to albumin in your blood and keeps going for about 8 days. The community calls this “set it and forget it” — one or two injections per week instead of daily pinning. This sustained release keeps IGF-1 elevated 200-300% above normal for days at a time. But there’s a catch: some users warn about “GH bleed” — the non-stop signal to the pituitary that doesn’t mimic the body’s natural pulse rhythm. The community is split: some love the convenience and strong results, others say the pulse-based approach (without DAC) is more natural and sustainable.

Why People Are Interested

• Fewer injections, same GH benefits. Inject 1-2 times per week instead of 1-3 times daily with the no-DAC version. Perfect for people who hate frequent pinning.
• Stronger IGF-1 elevation. The sustained signal drives higher and longer IGF-1 levels — translating to better recovery, fat loss, and anti-aging effects.
• Round-the-clock repair mode. Instead of GH pulses, you get a constant elevated baseline — ideal for healing from chronic injuries.
• Great for bulking or recovery phases. Users report steady lean mass gains and faster injury turnaround compared to the no-DAC version.

Popular Combinations

• CJC-DAC + GHRP-6: The GH bleed from DAC plus the hunger spike from GHRP-6 — a bulker’s dream stack for eating more and growing more.
• CJC-DAC + Ipamorelin: The cleaner alternative — DAC provides the sustained GHRH signal and Ipamorelin adds GH pulses without hunger.
• CJC-DAC + GHRP-2: Maximum GH output — the most aggressive secretagogue combo, but watch for cortisol and prolactin.
• CJC-DAC + MK-677: The “GH maximizer” stack — oral MK-677 plus injectable CJC-DAC for the highest possible secretagogue-driven IGF-1.

⚠️ Sourced from public forums (Reddit r/Peptides, r/Biohackers), fitness communities, and peptide blogs. The “GH bleed” concern (sustained non-pulsatile GH elevation) is a major community debate with no clinical resolution. Community protocols are experimental. This information is for awareness only.