CJC-1295 Without DAC

CJC-1295 Without DAC (also called Mod GRF 1-29) is a modified form of growth hormone-releasing hormone (GHRH). It stimulates your pituitary gland to release more of your own natural growth hormone — working with your body’s own GH pulses rather than replacing them. Supplied as lyophilized powder with ≥98% purity (HPLC-verified).

How It Works

Your body releases growth hormone in natural pulses, typically at night. CJC-1295 without DAC amplifies these pulses. It binds to GHRH receptors on the pituitary and increases both the size and frequency of GH releases — making your natural pulses stronger and longer-lasting.

Research Data

• GH pulse amplification: Studies show CJC-1295 increases peak GH pulse amplitude by 2 to 7 times, depending on dose — producing stronger GH surges during natural release windows.
• IGF-1 increase: Research shows sustained IGF-1 elevation of 50-100% above baseline with continued use, indicating meaningful downstream tissue effects.
• Natural pulse pattern: Because it amplifies existing pulses rather than flooding receptors, it maintains the body’s natural GH rhythm — important for receptor sensitivity.
• Short half-life: The “without DAC” version has a half-life of about 30 minutes, making it suitable for pulse-timing research applications.
• Sleep support: By enhancing nocturnal GH pulses, it supports the body’s natural repair processes that occur during deep sleep.

Research Applications

• GHRH receptor pharmacology
• Pulsatile hormone release research
• GH/IGF-1 axis studies
• Sleep-related hormone physiology

Product Specifications

• Purity: ≥98% (HPLC)
• Form: Lyophilized powder
• Solubility: Reconstitute in sterile bacteriostatic water

Storage & Handling

• Store lyophilized peptide at -20°C, protected from light and moisture.
• After reconstitution, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.

Disclaimer: This product is intended exclusively for laboratory and research purposes. It is not a drug, dietary supplement, or food product. Not for human or veterinary use.

What the Internet Says

This is what online communities discuss about this compound. Not medical advice, not a recommendation — just what people are saying. For laboratory research use only.

Community Buzz

In fitness, anti-aging, and lookmaxing communities, CJC-1295 without DAC (also called Mod GRF 1-29) is half of what many call the “gold standard” of GH secretagogues. It’s almost never discussed alone — it’s always paired with Ipamorelin to create the iconic “CJC/IPA stack.” Think of CJC as the signal and Ipa as the trigger: CJC tells the pituitary “release more GH,” and Ipa pulls the trigger to make it happen. Together, they can pump out 2-7x more growth hormone per pulse than your body does naturally. The community calls this “the secretagogue route” — tapping into your own natural GH system instead of flooding it with synthetic HGH.

Why People Are Interested

• Leaner body without the side effects. Users report losing fat and gaining lean muscle gradually — not overnight, but steadily — without the bloating or blood sugar issues that can come with HGH.
• Deep, restorative sleep. Taken before bed, it boosts the natural GH surge that happens during deep sleep. Users wake up feeling “truly rested.”
• Recovery improves noticeably. Less soreness after workouts, faster healing from nagging injuries, more energy day to day.
• Skin and hair look healthier. Collagen production improves over time — tighter skin, thicker hair, stronger nails. Part of the “anti-aging secretagogue approach.”

Popular Combinations

• CJC + Ipamorelin (“CJC/IPA”): The gold standard. Ipamorelin is chosen over other GHRPs because it doesn’t cause hunger, cortisol, or prolactin spikes — the cleanest partner for CJC.
• CJC/IPA + GHK-Cu: The “glow stack” — CJC/IPA for GH benefits, GHK-Cu for collagen and skin tightening.
• CJC/IPA + BPC-157 + TB-500: Adding healing peptides to the GH boost for comprehensive recovery.
• CJC/IPA before bed: The standard timing — taken fasted at night to amplify your body’s own overnight GH release.

⚠️ Sourced from public forums (Reddit r/Peptides, r/Biohackers), fitness communities, and peptide blogs. Community protocols are experimental. The “fasted state” requirement (no food 2 hours before or 30 minutes after) is critical in community discourse. This information is for awareness only.