Isotonitazepyne EU


Discover Isotonitazepyne: Powerful Pain Relief

Isotonitazepyne (N-pyrrolidino isotonitazene) is a potent synthetic opioid known for its exceptional pain-relieving capabilities. It acts on the µ-opioid receptors to provide quick and effective relief from severe and chronic pain, coupled with a sense of deep euphoria and relaxation.

With its remarkable potency, Isotonitazepyne is a critical tool in pain management but should be used with extreme caution. Proper understanding and respect for its power are essential for safe usage.

Experience advanced pain relief with Isotonitazepyne — handle with care.

For a safer and easier research this product is available also as e-Liquid:

Protonitazepyne and all other synthetic opioids sold on this website are intended for research and forensic applications.

This like all the products from EU RC are shipped on Tuesday by express mail without tracking number,
to European countries ONLY.

Isotonitazepyne (N-pyrrolidino isotonitazene) is a synthetic opioid and a novel derivative within the benzimidazole subclass of opioids, which have been developed to provide significant analgesic effects. This compound has a high affinity for the µ-opioid receptor, making it highly effective but also potentially very dangerous due to its potency.


Isotonitazepyne functions primarily as a full agonist at the µ-opioid receptor, the main site responsible for the analgesic, euphoric, and addictive effects of opioids. The efficacy of Isotonitazepyne in activating these receptors can result in profound analgesia, similar or superior to other potent opioids such as fentanyl.

Dosage and Administration

The appropriate dosage of Isotonitazepyne should be determined with extreme caution. Initial doses should be in the microgram range, owing to its high potency. Users and researchers should start with the smallest possible dose to gauge the effects and the individual’s response.


Users of Isotonitazepyne can expect effects typical of strong opioids, including:

  • Analgesia: Rapid onset of pain relief, particularly effective for severe and chronic pain.
  • Euphoria: A state of intense happiness and relaxation.
  • Sedation: Drowsiness and a deep sense of calm.

Side Effects

As with other opioids, Isotonitazepyne can cause a range of side effects:

  • Respiratory depression: Potentially life-threatening reduction in the urge to breathe.
  • Nausea and vomiting: Common with many opioids, especially at higher doses.
  • Constipation: A frequent complication of chronic opioid use.

Harm Reduction Tips

To minimize risk, users should:

  • Never use alone; have someone nearby who can administer naloxone.
  • Start with very low doses to assess tolerance.
  • Avoid combining with alcohol or benzodiazepines due to increased risk of respiratory depression.

In conclusion, while Isotonitazepyne may offer potent pain relief and euphoric effects, it must be approached with the highest degree of caution due to its extreme potency and risk of overdose.



Isotonitazepyne and all other synthetic opioids sold on this website are intended for research and forensic applications.

Isotonitazepyne Pure for REAL EXPERT ONLY.

Isotonitazepyne Mix 1:3 has been made with Inositol for a safer research.

Isotonitazepyne e-Liquid is 10mg/ml in 50-50 VG-PG.
The formula has been made for a safer and enjoyable research.


Select product

Pure, Mixed 1:3


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