Overview:
N-Desethylisotonitazene is a novel synthetic opioid, derived from the benzimidazole family. It’s an active metabolite of etonitazene and exhibits similar opioid effects.
Pharmacology:
This compound acts as a potent agonist at the mu-opioid receptors, leading to significant analgesic effects. It’s known for its strong efficacy in pain management but also carries a high risk for abuse and dependency.
Usage and Dosage:
Given its potency, dosages should be handled with extreme caution. There is little formal research on safe dosage levels, so any use should be guided by utmost caution and a thorough understanding of opioid pharmacology.
Side Effects and Risks:
Users may experience typical opioid side effects like nausea, drowsiness, and respiratory depression. The risk of severe respiratory depression and overdose is particularly high, especially when mixed with other CNS depressants.
Harm Reduction:
Users are strongly advised to have Naloxone accessible as a countermeasure against overdose. It’s critical to avoid using this substance in conjunction with other depressants and to always prioritize safety in research settings.
N-Desethylisotonitazene and all other synthetic opioids sold on this website are intended for research and forensic applications
English 
Dutch 
Spanish 
French 
Finnish 
German
Peter –
This was a really strong and potent opioid and I got really surprised by its potency! They act a bit short so it is important not to refill too early due to its heavy potency! Be careful when you do your research! It is definitely worth the money and Ivolabs are very serious and deliver high quality chemicals with delivery times that are very good! I strongly recommend this, especially the blotters to have a safe research!
IVOLABS –
Thank you for sharing your experience! It’s great to hear that you found the product to be of high quality and potent, but it’s also important to emphasize the need for caution, especially with strong opioids. Their short duration of action can indeed be tricky, so it’s crucial to avoid redosing too soon to prevent potential risks.
It’s also good to know that you had a positive experience with Ivolabs in terms of delivery and quality. However, as you mentioned, safety should always be the top priority when conducting research with such substances. Using blotters can indeed help with precise dosing, but always ensure you have the proper knowledge, tools, and harm reduction practices in place.
Stay safe and responsible in your research!
Padraig Conaghan –
Very strong. Does require re-dosing, but this does not detract from the product- just be careful! Would recommend to opioid users who like getting blasted. Also, does not appear to ‘pop’ on standard urine-dip drug tests (this is anecdotal, please do not simply take my word for it). Great product overall in terms of getting a nod on. Thanks!
IVOLABS –
Thanks for sharing your experience! It’s good to hear that you found the product effective and strong, but your reminder about caution is key—especially with re-dosing, as it can increase risks significantly. It’s also interesting to hear your anecdotal note about drug tests, though, as you mentioned, it’s always best to take such information with caution and not rely on it entirely.
For those seeking potent effects, it sounds like this product delivers, but safety should always come first. Opioids, especially strong ones, carry serious risks, including dependency and overdose. Always measure carefully, avoid frequent re-dosing, and prioritize harm reduction practices.
Thanks again for the review, and stay safe out there! If you or others are using such substances, please consider having naloxone on hand and researching harm reduction resources. Take care!