VIP
Price range: €360.00 through €600.00
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide that functions as both a neurotransmitter and a hormone throughout the body. It plays a critical role in regulating inflammation, immune function, smooth muscle relaxation, and circadian rhythms. Supplied as lyophilized powder with ≥98% purity (HPLC-verified).
How It Works
VIP binds to VPAC1 and VPAC2 receptors throughout the body. In the immune system, it shifts the response from Th1 (inflammatory) toward Th2 and regulatory T-cell profiles — making it one of the body’s key anti-inflammatory signals. In the gut and blood vessels, it promotes smooth muscle relaxation, and in the brain, it acts as a neurotransmitter involved in circadian rhythm control.
Research Data
- Immune regulation: VIP suppresses inflammatory cytokines (TNF-α, IL-6, IL-12) while promoting anti-inflammatory cytokines (IL-10) and regulatory T cells — a comprehensive immune-modulating profile.
- Autoimmune disease: Research shows VIP protects against and treats autoimmune conditions including rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis in animal models — by restoring immune balance.
- Circadian rhythm: VIP is essential for synchronizing the brain’s master clock (suprachiasmatic nucleus) — making it fundamental to sleep-wake cycle research.
- Vasodilation: As the name suggests, VIP is a powerful vasodilator that relaxes blood vessels and increases blood flow — the most potent endogenous vasodilator peptide known.
- Lung protection: Investigated for protecting lung tissue in acute respiratory distress and pulmonary hypertension models, including COVID-19-related research.
- Neuroprotection: Protects neurons from inflammation and oxidative stress, with research in Parkinson’s disease and neurodegeneration models.
- Gut function: Regulates intestinal motility, secretion, and barrier function — integration of the neuro-immune-gut axis.
Research Applications
- Immune modulation and autoimmune disease models
- Circadian rhythm and chronobiology
- Neuroprotection and neuroinflammation
- Vascular biology and smooth muscle research
Product Specifications
- Purity: ≥98% (HPLC)
- Form: Lyophilized powder
- Molecular Weight: ~3,326 Da
- Solubility: Reconstitute in sterile bacteriostatic water
Storage & Handling
- Store lyophilized peptide at -20°C, protected from light and moisture.
- After reconstitution, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.
Disclaimer: This product is intended exclusively for laboratory and research purposes. It is not a drug, dietary supplement, or food product. Not for human or veterinary use.
What the Internet Says
This is what online communities discuss. Not medical advice — for laboratory research use only.
Community Buzz
VIP is “the inflammation calmer” — a small but dedicated user base uses it for chronic inflammation, respiratory conditions, and immune regulation. Users with psoriasis, chronic sinus inflammation, and lung issues report improvement. One critical warning from the community: dose carefully. A reported accidental 600mcg overdose (6x the normal 100mcg) caused severe flushing, racing heart, and hypertensive crisis-like symptoms for 2 hours. The community pairs it with KPV for combined anti-inflammatory protocols and sometimes with bronchogen for lung-specific applications.
Why People Are Interested
- Calms systemic inflammation. Reduces inflammatory markers across multiple body systems.
- Respiratory and lung function support. Users with chronic sinus and lung issues report improvement.
- Immune regulation. Helps balance immune responses in chronic inflammatory conditions.
⚠️ Dosing errors can cause severe acute reactions — start low, titrate carefully. Community protocols are experimental. This information is for awareness only.
| Dosage |
10mg*10vials ,5mg*10vials |
|---|
Shipping & Delivery
All peptide products are shipped directly from our fulfillment center in China.
Delivery Time: 6 to 12 business days worldwide.
Tracking: A tracking number is provided via email once your order has been dispatched.
For any questions regarding your shipment, please contact our support team.
All peptide products are supplied as a lyophilized (freeze-dried) powder in sterile glass vials. Lyophilization preserves the peptide's structural integrity and biological activity during transport and storage. The powder must be reconstituted with an appropriate solvent before use in research protocols.
Recommended Solvent
For most peptide research applications, we recommend using Bacteriostatic Water (BAC) — sterile water containing 0.9% benzyl alcohol as a bacteriostatic agent. BAC water helps maintain sterility after reconstitution and is suitable for multi-dose research protocols.
Order Bacteriostatic Water (BAC) →
Reconstitution Protocol
- Prepare: Clean your work surface and ensure all materials (vial, BAC water, syringes) are handled in a sterile manner.
- Calculate: Determine the desired concentration by dividing the peptide mass (mg) by the volume of BAC water added (mL). For example, adding 2 mL of BAC water to a 5 mg vial yields a concentration of 2.5 mg/mL.
- Reconstitute: Using a sterile syringe, draw the calculated volume of BAC water. Insert the needle through the rubber stopper at an angle and slowly inject the solvent down the inner wall of the vial — avoid directing the stream directly onto the powder to prevent foaming.
- Dissolve: Gently swirl the vial (do not shake) until the powder is fully dissolved. Most peptides dissolve within 1-2 minutes. A clear, colorless solution indicates complete dissolution.
- Aliquot: For long-term use, transfer the reconstituted solution into sterile aliquots to avoid repeated freeze-thaw cycles of the original vial.
Post-Reconstitution Storage
- Store reconstituted peptide solution at 2-8°C for short-term use (up to 7 days).
- For extended storage, aliquot and freeze at -20°C. Avoid repeated freeze-thaw cycles.
- Always label aliquots with peptide name, concentration, date, and storage conditions.
Note: The optimal solvent and reconstitution protocol may vary depending on the specific peptide and research application. Researchers should consult peptide-specific literature for solubility guidance.
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Discreet EU Shipping & Quality Assurance
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We maintain strict quality control standards with third-party laboratory verification for every batch. Our lyophilized peptides are packaged under controlled conditions to ensure stability during shipping and storage. Detailed reconstitution and handling information is provided with every product to support accurate laboratory research protocols.
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